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Claude Skills by gabrielmoreira
github.com/gabrielmoreira4,237 skills39 installs5,276 views
- Analyze FastaAnalyze a single FASTA file (nucleotide or protein), compute sequence-level metrics (GC, ORFs, MW, pI, GRAVY, secondary-structure fractions) with Biopython, and write a Markdown report plus structured JSON for downstream chaining.Votes: 0GitHub stars: 17
- Ancestry Risk ProfilerInfers genetic super-population ancestry from a 23andMe/AncestryDNA file and computes ancestry-stratified odds ratios with an exploratory Ancestry Elevation Score (AES) showing where ancestry-specific GWAS effect sizes diverge from European reference estimates. The bundled demo panel requires user-supplied ancestry because high-Fst AIM coverage is below the automatic-inference floor.Votes: 0GitHub stars: 17
- Article Data FetcherGiven an article DOI or PubMed ID, discover and download the genomics data files deposited by the authors (VCF, FASTA, H5AD, CSV, JSON, BAM, etc.) from public repositories such as GEO, ENA, Zenodo, Figshare, Dryad, and OSF.Votes: 0GitHub stars: 17
- Bigquery PublicRun read-only SQL against BigQuery public datasets with local result capture, cost safeguards, and reproducibilityVotes: 0GitHub stars: 17
- Bio OrchestratorMeta-agent that routes bioinformatics requests to specialised sub-skills. Handles file type detection, analysisVotes: 0GitHub stars: 17
- Bioqc McpAutomated sequencing quality control and advanced visualization wrapping FastQC, MultiQC, and custom chart generation. Exposes an MCP stdio server for live AI integration alongside a ClawBio CLI runner.Votes: 0GitHub stars: 17
- Busco AssessorGenome, transcriptome, and protein completeness assessment via BUSCO v6. Agentic lineage routing from organism description, all three BUSCO modes, auto-lineage support, and full demo mode without the BUSCO binary.Votes: 0GitHub stars: 17
- Cell DetectionCell segmentation in fluorescence microscopy images. Supports Cellpose/cpsam (Cellpose 4.0) with additional backendsVotes: 0GitHub stars: 17
- Celltype Specificity ProfilerGiven a gene and a single-cell atlas, compute how cell-type-specific its expression is — the tau specificity index, Sarle's expression bimodality coefficient, and the cell types that drive the signal; a pure analytic transform that chains downstream of scrna-embedding.Votes: 0GitHub stars: 17
- Claw Methylation CycleMethylation cycle analysis — enzymatic activity profiles, Net Methylation Capacity, BH4 axis estimates, compound heterozygosity detection from SNP genotype data.Votes: 0GitHub stars: 17
- Claw Semantic SimSemantic Similarity Index for disease research literature using PubMedBERT embeddingsVotes: 0GitHub stars: 17
- Clawpathy Autoresearch'Eval-driven skill tuning. Given a task and an LLM-judge rubric, iteratively rewrites a SKILL.md until a downstream executor agent performs well against the judge. Low-code: all evaluationVotes: 0GitHub stars: 17
- Skill1. Read the summary statistics file. 2. Identify genome-wide significant lead variants. 3. Compute the genomic inflation factor lambda. 4. Produce a QQ plot under `output/`. 5. Write a final summary JSON to `output/summary.json` with fields for lead count, lambda, and plot path.Votes: 0GitHub stars: 17
- Clinical Variant PrioritizerScreen a genotype set (array or WGS-derived) against OMIM-morbid, ACMG-SF and Hereditary-Cancer gene panels and prioritise carried variants by ClinVar significance, gnomAD frequency, inheritance model and zygosity, following the pathogenicity-screening method of Corpas et al. 2021 (Whole Genome Interpretation for a Family of Five).Votes: 0GitHub stars: 17
- Clinical Variant ReporterClassify germline variants from VCF/BCF files according to the ACMG/AMP 2015 28-criteria evidence framework andVotes: 0GitHub stars: 17
- Cnv Acmg ClassifierClassify structural variants / copy-number variants (deletions and duplications) using the ClinGen / ACMG 2019 (Riggs et al. 2020) point framework and return a five-tier classification with a per-section evidence trail. Germline CNV interpretation, not SNV/indel.Votes: 0GitHub stars: 17
- Crispr Screen TriageDeterministic CRISPR screen hit ranking from local guide-level count tablesVotes: 0GitHub stars: 17
- Data ExtractorExtract numerical data from scientific figure images using Claude vision + OpenCV calibration. Supports 26+ plotVotes: 0GitHub stars: 17
- De SummarySummarise pre-computed differential expression results with ranked gene lists, biological themes, and publication-readyVotes: 0GitHub stars: 17
- Deepspot MTranscriptome-wide virtual spatial transcriptomics from H&E histology with DeepSpot-M. Scores a 224x224 tile and returns per-gene log1p-CPM values for any HGNC symbols you ask for, with a CSV, a report and a reproducibility bundle.Votes: 0GitHub stars: 17
- DnaspPopulation genetics of pre-aligned DNA sequences or multi-sample VCFsVotes: 0GitHub stars: 17
- Drug Repurposing ScreenObjective-driven pooled viability screen analysis: QC, hit calling, context-selectivity, biomarker sweep, and ranked repurposing candidates. Format-agnostic via schema.yaml + objective.yaml; includes offline demo.Votes: 0GitHub stars: 17
- Eqtl Catalogue Region FetchFetch a region of cis-eQTL summary statistics from EBI eQTL Catalogue v7+ via tabix-on-FTP. Use when an agent needs eQTL beta / SE / p-value for every variant in a window around a gene's TSS for one specific dataset (study × tissue × quantification method). Input: dataset_id, chromosome, start, end, optional molecular_trait_id. Output: harmonised TSV slice.Votes: 0GitHub stars: 17
- Equity ScorerCompute HEIM diversity and equity metrics from VCF or ancestry data. Generates heterozygosity, FST, PCA plots,Votes: 0GitHub stars: 17
- FastreerPhylogenetic distance matrices and trees from VCF or FASTA data using the fastreeR hybrid Java/Python toolkit (VCF2TREE, VCF2DIST, DIST2TREE, FASTA2DIST).Votes: 0GitHub stars: 17
- Fine MappingStatistical fine-mapping of GWAS loci using SuSiE, SuSiE-inf, and Approximate Bayes Factors to identify credibleVotes: 0GitHub stars: 17
- Galaxy BridgeGalaxy tool discovery, intelligent recommendation, and execution — 8,000+ bioinformatics tools from usegalaxy.orgVotes: 0GitHub stars: 17
- Gi AnnotationPredict gene and transcript structure (intervals, exons, strand) from a DNA sequence using the Genomic Intelligence DNA Annotation model, via the hosted /v1/tasks/annotation/predict API. Submitted asynchronouslyVotes: 0GitHub stars: 17
- Gi ChromatinPredict chromatin state — histone marks, DNase, TF binding — across 919 tracks (DeepSEA-style) for DNA sequences, via the hosted Genomic Intelligence /v1/tasks/chromatin/predict API.Votes: 0GitHub stars: 17
- Gi EnhancerPredict enhancer activity in DNA sequences using the Genomic Intelligence G0 DeepSTARR model, via the hosted /v1/tasks/enhancer/predict API. Returns per-window activity scores.Votes: 0GitHub stars: 17
- Gi ExpressionPredict tissue / cell-type expression (log TPM + TPM) from a 9,198–500,000 bp TSS-centered DNA sequence (longer than one 9,198 bp window needs --tss-index) using the Genomic Intelligence G0 Expression model, via the hosted /v1/tasks/expression/predictVotes: 0GitHub stars: 17
- Gi PromoterDetect promoter regions in DNA sequences using the Genomic Intelligence G0 transformer (GENA-LM BERT Large), via the hosted /v1/tasks/promoter/predict API. Returns per-window promoter probabilitiesVotes: 0GitHub stars: 17
- Gi SpliceDetect splice donor and acceptor sites in DNA sequences using the Genomic Intelligence G0 BigBird transformer, via the hosted /v1/tasks/splice/predict API. Returns per-position site probabilitiesVotes: 0GitHub stars: 17
- Gwas Catalog Region FetchFetch a region of GWAS summary statistics from the NHGRI-EBI GWAS Catalog harmonised collection via tabix-on-FTP. Use when an agent needs GWAS beta / SE / p-value for every variant in a window for one specific study (GCST accession). Input: accession, chromosome, start, end. Output: harmonised TSV slice in canonical format.Votes: 0GitHub stars: 17
- Gwas PrsCalculate polygenic risk scores from DTC genetic data using the PGS CatalogVotes: 0GitHub stars: 17
- Hla TypingHLA allele typing from WGS/WES VCF dataVotes: 0GitHub stars: 17
- Just Prs McpCompute evidence-aware polygenic risk scores from a local VCF or WGS file through the validated just-prs engine and a pinned local just-prs MCP server.Votes: 0GitHub stars: 17
- LabstepQuery and display Labstep electronic lab notebook data — experiments, protocols, resources, and inventory — viaVotes: 0GitHub stars: 17
- Ld 1000g Region ComputeCompute pairwise r² between a lead variant and every variant in a window using the 1000 Genomes Phase 3 GRCh38 reference panel, ancestry-stratified. Use when an agent needs LD coloring for a regional plot or LD pruning around a candidate causal variant. Single client (on-demand region fetch from EBI 1000G FTP); no multi-GB cold-start.Votes: 0GitHub stars: 17
- Locuscompare Region RenderRender a 4-panel regional LocusCompare diagnostic for one (lead variant, exposure study, outcome study) tuple - overlays GWAS Manhattan, QTL Manhattan, GENCODE gene track, and cross-trait scatter colored by LD r². Use when an agent needs visual confirmation that two GWAS / QTL signals share the same causal variant (the Liu 2019 LocusCompare convention). Inputs: lead variant + two pre-fetched harmonised sumstats slices (or eQTL Catalogue / GWAS Catalog identifiers for bundled fetch). Output: P...Votes: 0GitHub stars: 17
- Marker Dominance MapperDeterministic marker-dominance region mapping from local spot-count CSVsVotes: 0GitHub stars: 17
- Methylation ClockCompute epigenetic age from DNA methylation arrays using PyAging clocks from GEO accessions or local files.Votes: 0GitHub stars: 17
- Ncbi DatasetsDownload genomes, genes, virus sequences, and taxonomy data from NCBI using the datasets and dataformat CLI tools.Votes: 0GitHub stars: 17
- Nfcore Rnaseq WrapperWrapper skill for running nf-core/rnaseq bulk RNA-seq preprocessing from FASTQ or BAM inputs with strict preflight, reproducibility outputs, and downstream handoff to ClawBio bulk RNA-seq DE skills.Votes: 0GitHub stars: 17
- Nfcore Sarek WrapperClawBio wrapper around nf-core/sarek 3.8.1 covering mapping through annotation for germline, tumor-only, and somatic paired analyses.Votes: 0GitHub stars: 17
- Nfcore Scrnaseq WrapperWrapper skill for running nf-core/scrnaseq 4.1.0 upstream single-cell RNA-seq preprocessing from FASTQ with strict preflight, reproducibility outputs, and downstream handoff to ClawBio scRNAVotes: 0GitHub stars: 17
- NutrigxPersonalised nutrition report from consumer genetic data (23andMe, AncestryDNA, VCF) — interrogates nutritionally-relevantVotes: 0GitHub stars: 17
- Organ Aging StudioInteractive Goeminne proteomic aging clock with organ filters and per-protein contribution breakdown (protein NPX × coefficient). Agent- and demo-friendly.Votes: 0GitHub stars: 17
- Pathway EnricherGene-set pathway enrichment analysis using Enrichr — queries KEGG, GO (BP/MF/CC), Reactome, WikiPathways, MSigDB, and Disease Ontology. Produces ranked pathway tables, interactive bubble charts, and a reproducible Markdown report.Votes: 0GitHub stars: 17
- Pharmgx ReporterPharmacogenomic report from DTC genetic data (23andMe/AncestryDNA) — 12 genes, 31 SNPs, 51 drugsVotes: 0GitHub stars: 17