Installs into .claude/skills of the current project.
Are you the author of 1506 Usage Guide 4e816121?
Add the live security badge to your README. It updates with every re-scan.
[](https://www.skillsdirectory.com/skills/tools-only-1506-usage-guide-4e816121)
# CLIP Motif Analysis - Usage Guide
## Overview
Find enriched sequence motifs at CLIP-seq binding sites to characterize RBP binding preferences.
## Prerequisites
```bash
conda install -c bioconda homer meme bedtools
```
## Quick Start
- "Find de novo motifs at binding sites"
- "Check for known RBP motifs"
## Example Prompts
> "Run HOMER motif analysis on my CLIP peaks"
> "Find enriched 6-8mer motifs"
## What the Agent Will Do
1. Extract peak sequences (bedtools getfasta)
2. Run de novo motif discovery
3. Compare to known RBP motifs
4. Report enriched motifs
## Tips
- **Use -rna flag** for RNA motifs in HOMER
- **Background** should match GC content
- **6-8 nt motifs** are typical for RBPs
