Genomics Variants

---
title: locus-to-gene-mapper-skill
aliases:
  - locus to gene mapper skill
tags:
  - skill
  - domain/genomics-variants
domain: genomics-variants
status: untried
source: skills/locus-to-gene-mapper-skill/SKILL.md
created: 2026-08-07
---

# locus-to-gene-mapper-skill

> [!info] What it does
> Map GWAS loci to ranked candidate genes using a deterministic multi-skill chain (EFO -> GWAS -> coordinates -> Open Targets L2G/coloc -> eQTL -> burden/coding context), with reproducible tables and optional figures. Use when a user provides a trait/EFO term and/or lead variants and needs locus-to-gene prioritization for downstream biology decisions.

**Source:** [skills/locus-to-gene-mapper-skill/SKILL.md](../../../skills/locus-to-gene-mapper-skill/SKILL.md)  ·  **Domain:** [Genomics, Variants & Population Genetics](../../maps/genomics-variants.md)  ·  **Table:** [skills.base](../../skills.base)  ·  **Index:** [Skills Index](../../index.md)

## Related skills

_None auto-detected. Add your own links here, e.g. `[[scanpy]]`._

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## Notes