Evaluates multimodal large language models' ability to perform visual-to-clinical reasoning on brain imaging data. It probes capabilities ranging from basic anatomical identification to complex multi-stage clinical decision-making and prognosis prediction. Use when the user wants to benchmark on OmniBrainBench, or asks about evaluating this task. Reports accuracy.
Scanned 9/11/2026
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---
name: omnibrainbench-eval
description: Evaluates multimodal large language models' ability to perform visual-to-clinical reasoning on brain imaging data. It probes capabilities ranging from basic anatomical identification to complex multi-stage clinical decision-making and prognosis prediction. Use when the user wants to benchmark on OmniBrainBench, or asks about evaluating this task. Reports accuracy.
metadata:
skill_kind: dataset_eval
source_arxiv: 2511.00846
bibtex_key: peng2025omnibrainbench
confidence: high
---
# omnibrainbench-eval
> OmniBrainBench: A Comprehensive Multimodal Benchmark for Brain Imaging Analysis Across Multi-stage Clinical Tasks — Peng et al. (2025) (arXiv:2511.00846, 2025)
## What this evaluates
Evaluates multimodal large language models' ability to perform visual-to-clinical reasoning on brain imaging data. It probes capabilities ranging from basic anatomical identification to complex multi-stage clinical decision-making and prognosis prediction.
## Datasets
- **OmniBrainBench** — total ?; splits: test (-1)
## Metrics
- `accuracy` **(primary)** — range: percent
- Percentage of correctly answered questions across all 15 clinical subtasks. Calculated as (number of correct predictions / total number of questions) * 100.
## Input / output format
**Input**: Brain imaging images (spanning 15 clinical modalities) paired with clinical questions or prompts requiring visual-to-clinical reasoning.
**Output**: Text-based answers to clinical questions, evaluated for correctness against ground-truth physician responses.
## Scoring recipe
```python
correct = 0
total = 0
for task in tasks:
for question, gold in task.items():
pred = model.generate(image, question)
if pred == gold:
correct += 1
total += 1
accuracy = (correct / total) * 100
```
## Common pitfalls
- Assuming high scores in visual perception tasks translate to reliable clinical reasoning capabilities.
- Treating benchmark accuracy as a substitute for real-world clinical validation, despite the paper's explicit warning that it cannot replace final clinical evaluation.
- Overlooking task-specific variability; models may excel in structured tasks but fail significantly in complex reasoning tasks like risk stratification.
## Evidence (verbatim from paper)
> We conduct extensive experiments on MLLMs across five specialized clinical tasks with 15 secondary subtasks to summarize their current capabilities and limitations... The physician achieves an average accuracy of 91.35% across all tasks, whereas the highest-performing model, Gemini-2.5-Pro, attained only 66.58%—reflecting a substantial performance gap of approximately 24.77%.
## Citation
```bibtex
@misc{peng2025omnibrainbench,
title={OmniBrainBench: A Comprehensive Multimodal Benchmark for Brain Imaging Analysis Across Multi-stage Clinical Tasks},
author={Peng et al. (2025)},
year={2025},
note={arXiv:2511.00846}
}
```
- arXiv: 2511.00846
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