MAGeCK CRISPR screen analysis skill for gene essentiality scoring
Scanned 9/2/2026
Install to Claude Code
Skills Directorynpx -y skills add a5c-ai/babysitter --skill mageck-crispr-analyzer --agent claude-codeInstalls into .claude/skills of the current project.
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---
name: mageck-crispr-analyzer
description: MAGeCK CRISPR screen analysis skill for gene essentiality scoring
allowed-tools:
- Read
- Write
- Glob
- Grep
- Edit
- WebFetch
- WebSearch
- Bash
metadata:
version: "1.0"
category: bioinformatics
tags:
- specialized
- crispr
- screening
- essentiality
graph:
domains: [domain:bioinformatics]
specializations: [specialization:biomedical-informatics]
skillAreas: [skill-area:statistical-analysis, skill-area:python-data-pipelines, skill-area:data-analysis]
workflows: [workflow:experiment-design]
roles: [role:research-scientist, role:biomedical-engineer]
---
# MAGeCK CRISPR Analyzer Skill
## Purpose
Provide MAGeCK CRISPR screen analysis for gene essentiality scoring.
## Capabilities
- Guide read counting
- Normalization and QC
- Gene-level analysis
- Pathway enrichment
- MLE model for complex designs
- Visualization outputs
## Usage Guidelines
- Count guides accurately from sequencing data
- Normalize counts appropriately
- Calculate gene-level scores
- Enrich for biological pathways
- Use MLE for complex experimental designs
- Generate informative visualizations
## Dependencies
- MAGeCK
- BAGEL
- CRISPResso2
## Process Integration
- CRISPR Screen Analysis (crispr-screen-analysis)
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