Development

Navigate protein structure hierarchy using Biopython Bio.PDB SMCRA model. Use when accessing models, chains, residues, and atoms, iterating over structure levels, or extracting sequences from PDB files.

Modify protein structures using Biopython Bio.PDB. Use when transforming coordinates, removing atoms or residues, adding new entities, modifying B-factors and occupancies, or building structures programmatically.

Build a custom durable AI agent with full control over streamText options, provider configs, and tool loops. Compatible with the Workflow Development Kit.

Type-safe environment variable validation using Zod with a Drizzle-like schema API. Supports server/public fields, feature flags, either-or constraints, and client-side protection.

Configure Prettier for code formatting and TypeScript for typechecking. Includes VSCode settings and EditorConfig for consistent code style. Skips ESLint/Biome to avoid config complexity.

Guidelines for building scalable, SEO-friendly applications with Next.js (App Router).

Essential guidelines for writing modern, type-safe, and idiomatic Python 3 code.

Transcribe DNA to RNA and translate to protein using Biopython. Use when converting between DNA, RNA, and protein sequences, finding ORFs, or using alternative codon tables.

Slice, extract, and concatenate biological sequences using Biopython. Use when extracting subsequences, joining sequences, or manipulating sequence regions by position.

Build a chat list page with search, rename, and delete functionality. Uses nuqs for URL-synced filters and deep-linkable modal dialogs.

Calculate sequence properties like GC content, molecular weight, isoelectric point, and GC skew using Biopython. Use when analyzing sequence composition, computing physical properties, or comparing sequences.

Create and manipulate Seq, MutableSeq, and SeqRecord objects using Biopython. Use when creating sequences from strings, modifying sequence data in-place, or building annotated sequence records.

Generate reverse complements and complements of DNA/RNA sequences using Biopython. Use when working with opposite strands, primer design, or converting between template and coding strands.

Add server-side route protection to enforce authentication on specific pages while keeping others public.

Add a complete account settings page with profile editing, password changes, email updates, session management, and account deletion.

Write biological sequences to files (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when saving sequences, creating new sequence files, or outputting modified records.

Read biological sequence files (FASTA, FASTQ, GenBank, EMBL, ABI, SFF) using Biopython Bio.SeqIO. Use when parsing sequence files, iterating multi-sequence files, random access to large files, or high-performance parsing.

Add email verification, password reset, and account management emails to Better Auth using Resend.

Add UI components and pages for authentication flows including sign in, sign up, forgot password, reset password, and email verification.

Handle paired-end FASTQ files (R1/R2) using Biopython. Use when working with Illumina paired reads, synchronizing pairs, interleaving/deinterleaving, or filtering paired data.

Convert between sequence file formats (FASTA, FASTQ, GenBank, EMBL) using Biopython Bio.SeqIO. Use when changing file formats or preparing data for different tools.

Filter and select sequences by criteria (length, ID, GC content, patterns) using Biopython. Use when subsetting sequences, removing unwanted records, or selecting by specific criteria.

Complete setup guide for a Next.js app with Shadcn UI, Neon Postgres, Drizzle ORM, and AI SDK.

Complete authentication system with Better Auth, email verification, password reset, protected routes, and account management.