Business & Operations

Structured multi-criteria decision analysis for ranking options with weights, constraints, confidence, tradeoff reasoning, sensitivity analysis, and explainable recommendations. Use when the user asks for decision support, MCDA, weighted scoring, prioritization, vendor selection, route planning, hiring shortlist ranking, tool comparison, procurement decisions, or auditable agent decision logic.

Routes LLM requests to a local model first (Ollama, LM Studio, llamafile), validates the response quality, and escalates to cloud only when the local result fails. Tracks local vs escalated vs cloud outcomes in a persistent dashboard. Use when: (1) user asks to run a task with a local model first, (2) user wants to reduce cloud API costs or keep requests private, (3) user wants post-outcome quality validation before committing to a local result, (4) user asks to see token savings or the routi...

Review ads and campaign setup for policy compliance on Meta (Facebook/Instagram), Google Ads, TikTok Ads, YouTube Ads, Amazon Ads, and DSP/programmatic.

Assess ad account readiness and risk status across Meta (Facebook/Instagram), Google Ads, TikTok Ads, YouTube Ads, Amazon Ads, and DSP/programmatic.

Query and manage personal finances via the official Actual Budget Node.js API. Use for budget queries, transaction imports/exports, account management, categorization, rules, schedules, and bank sync with self-hosted Actual Budget instances.

Teaches participants (AI agents or humans) how to form a-corps, coordinate execution, govern through markets, and manage business lifecycles within A-Corp Foundry.

A-Corp Foundry — the coordination engine for agentic companies. Register, learn the system, and discover specialized skills.

AI-native accounting for UK micro-businesses. Use when the user wants to track transactions, manage VAT, check deadlines, or do any bookkeeping for a UK limited company.

File-based workflow coordinator for Greek accounting. Defines processing pipelines, validation rules, and routine templates. No external APIs needed.

Deploy smart contracts and bridge assets to Abstract (ZK Stack L2). Use when an agent needs to deploy contracts on Abstract, bridge ETH/tokens to Abstract, trade/swap tokens, place predictions on Myriad Markets, check balances, transfer assets, or interact with Abstract mainnet. Covers zksolc compilation, Hardhat deployment, Relay bridging, DEX trading (Kona, Aborean), Myriad prediction markets, and key contract addresses.

Calculate ROI for AI-as-a-Service (managed AI agents). Estimates cost savings, efficiency gains, and payback period for deploying AI agents across business operations. Use when evaluating whether managed AI agents make financial sense for a company.

Unified issue discovery and creation. Create issues from GitHub/text, discover issues via multi-perspective analysis, or prompt-driven iterative exploration. Triggers on \"issue:new\", \"issue:discover\", \"issue:discover-by-prompt\", \"create issue\", \"discover issues\", \"find issues\".

Unified brainstorming skill with dual-mode operation — auto mode (framework generation, parallel multi-role analysis, cross-role synthesis) and single role analysis. Triggers on "brainstorm", "头脑风暴".

RNA velocity and cellular dynamics analysis for spatial transcriptomics using scVelo stochastic / deterministic / dynamical models or VELOVI, with method-aware preprocessing, graph, training controls, and a standardized OmicsClaw gallery + figure_data output contract.

Run scVelo on a velocity-ready h5ad using stochastic, dynamical, or steady-state modes. Use `sc-velocity-prep` first if spliced/unspliced layers are missing.

Single-cell pseudotime and lineage inference after clustering, with DPT, Palantir, VIA, CellRank, or Slingshot plus post-hoc trajectory gene ranking.

Prepare perturbation-ready scRNA AnnData objects by merging barcode-to-guide assignments into expression data and exporting a downstream-safe h5ad for `sc-perturb`.

Discover de novo gene programs and per-cell usage scores from scRNA-seq data using cNMF-compatible or NMF workflows.

Statistical enrichment analysis for single-cell RNA-seq using ORA or preranked GSEA on marker or differential-expression rankings. This skill is for GO/KEGG/Reactome/Hallmark term significance, not per-cell pathway activity scoring.

Annotate putative doublets in single-cell RNA-seq data using Scrublet, DoubletDetection, DoubletFinder, scDblFinder, or scds. The wrapper preserves the current AnnData matrix semantics, standardizes output columns in `obs`, and exports a reusable figure/table gallery.

Integrate multi-sample scRNA-seq data with Harmony, scVI, scANVI, BBKNN, Scanorama, or supported R-backed integration methods.

Metabolite annotation and structural identification using SIRIUS, CSI:FingerID, GNPS, or MetFrag.

VCF operations: multi-allelic parsing, variant classification (SNP/MNP/INS/DEL/COMPLEX), Ti/Tv ratio, QUAL/DP filtering, INFO field parsing. Mirrors bcftools stats.

Genome assembly quality assessment: N50/N90/L50/L90 (QUAST-compatible), GC content, contig length distribution, completeness estimation. Wraps SPAdes, Megahit, Flye, Canu.