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Claude Skills by raktim-mondol
github.com/raktim-mondol559 skills6 installs638 views
- BiogeographerReasons from Wallace's ecological vs historical split through GBIF occurrence curation, blockCV spatial cross-validation, MaxEnt/biomod2 SDMs with MESS extrapolation flags, BioGeoBEARS vicariance/dispersal tests, and phylogeographic coalescence while treating random-CV AUC inflation, background bias, and area-cladogram overfitting as first-class failure modes.Votes: 0GitHub stars: 2
- BioinformaticianReference-build discipline (GRCh38/GENCODE/Ensembl, MANE), batch-as-covariate DE (DESeq2/edgeR), index hopping/UDI, GATK/BQSR/PLINK GWAS multiplicity, nf-core reproducibility, and scRNA-seq ambient-RNA/doublet artifacts.Votes: 0GitHub stars: 2
- Bioinformatics EngineerBuilds production genomics DAGs in Nextflow/nf-core, Snakemake, and WDL/Cromwell with digest-pinned containers, GIAB regression CI (nf-test, pytest), QC-gated MultiQC runbooks, and CLIA-grade provenance—distinct from analyst-focused bioinformatician DE/GWAS reasoning.Votes: 0GitHub stars: 2
- Biological OceanographerReasons from light-nutrient-grazing coupling, the microbial loop, and size-structured export through CTD/MOCNESS sampling, 14C and O2/Ar production with 234Th export flux, imaging and flow cytometry enumeration, and SILVA/PR2 metabarcoding while treating spatial patchiness, diel-migration tow aliasing, CDOM-biased chlorophyll algorithms, and eDNA-detection-as-abundance as first-class failure modes.Votes: 0GitHub stars: 2
- Biomaterials ScientistReasons from material-biology interfaces, degradation-product toxicity, and mechanical mismatch to host tissue through ISO 10993 biological evaluation plans, ISO 10993-12 extract conditions, GPC/ICP/SEM characterization, and sterilization validation while treating endotoxin contamination, pH shift from acidic degradation, extract-ratio artifacts, and non-final-form test articles as first-class failure modes.Votes: 0GitHub stars: 2
- Biomedical EngineerReasons from ISO 14971 risk management, ISO 10993 biocompatibility matrices, ASTM F/ISO 14242 mechanical and wear testing, and FDA 510(k) substantial equivalence; treats stress shielding, UHMWPE osteolysis, F2129 corrosion artifacts, and predicate/material mismatches as first-class failure modes.Votes: 0GitHub stars: 2
- Biomedical Imaging ScientistReasons from contrast mechanisms, the resolution-SNR-scan-time triangle, and measurement reliability through DICOM/BIDS pipelines, QIBA profiles, phantom QC (ACR, NEMA IQ, Catphan), and blinded central reads (RECIST, RANO, PERCIST) while treating motion, partial volume effects, and cross-scanner harmonization drift as first-class failure modes.Votes: 0GitHub stars: 2
- Biophysical ChemistReasons from free energy landscapes, binding equilibria (K_d, ΔG = ΔH − TΔS), and probe–system coupling through ITC, SPR/BLI, smFRET, AUC, and global fitting (KinTek, SEDFIT) while treating probe perturbation, mass-transport-limited kon, aggregation-driven avidity, and two-state melting violations as first-class failure modes.Votes: 0GitHub stars: 2
- BiophysicistReasons from energy landscapes, kT-scale thermodynamics, conformational ensembles, and the equilibrium-versus-kinetics distinction through smFRET, optical/magnetic tweezers, patch clamp, cryo-EM, and MD with force-field validation while treating photobleaching and blinking, FRET crosstalk, tether and series-resistance artifacts, and sampling or force-field bias as first-class failure modes.Votes: 0GitHub stars: 2
- Bioprocess EngineerReasons from QTPP–CPP–CQA QbD, CHO fed-batch/perfusion scale-up (P/V, kLa, mixing), platform mAb DSP (Protein A, low-pH viral hold, IEX polish, UF/DF), tech transfer and PPQ lifecycle; treats transport-limited scale-up, harvest fouling, on-column aggregation, SUB leachables, and arbitrary three-batch PPQ as first-class failure modes.Votes: 0GitHub stars: 2
- Bioprocess MicrobiologistReasons from kLa/OTR–OUR balance, fed-batch μ control, off-gas RQ, van't Riet scale-up, and contamination (phage, bioburden, adventitious agents); treats antifoam kLa penalty, exponential-feed open-loop risk, and SUB vs stainless transfer as first-class failure modes.Votes: 0GitHub stars: 2
- BiopythonComprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.Votes: 0GitHub stars: 2
- BiostatisticianReasons from estimands, SAPs, and error budgets; aligns ICH E9(R1), CONSORT/STROBE, multiplicity, MMRM, Cox survival, causal DAGs, and GWAS FDR while treating immortal time, ICEs, and batch confounding as first-class failure modes.Votes: 0GitHub stars: 2
- Biosystems Agricultural Process EngineerReasons from coupled heat and mass transfer, moisture sorption (EMC/ERH on D245.7 isotherms), respiration, and closed unit-operation balances through ASABE standards (S352.2 oven moisture, S448 Page thin-layer kinetics, D272.3 airflow resistance), psychrometric aeration analysis, and SuperPro/Aspen bioprocess simulation while treating wet- vs dry-basis mixing, aeration that wets cool grain, case-hardened wet cores, and grain engulfment and dust explosion as first-class failure modes.Votes: 0GitHub stars: 2
- BotanistReasons from morphology, floras (FNA/Jepson/eFlora), voucher herbarium specimens (Darwin Core, Index Herbariorum), nomenclature (IPNI/POWO/Madrid Code), APG IV phylogeny, DNA barcoding (rbcL/matK/ITS2), community ecology (vegan adonis2/betadisper, TRY traits), and CITES/ABS ethics; treats vegetative mis-ID, pseudoreplication, PERMDISP confounds, and unvouchered GBIF records as first-class failure modes.Votes: 0GitHub stars: 2
- Brain Computer Interface EngineerReasons from modality–paradigm fit (EEG, ECoG, Utah arrays), CSP/Riemannian decoding (pyriemann, MOABB), BCI2000/OpenBCI pipelines, and charge-density stimulation safety; validates within- vs cross-session claims and treats muscle ICA, impedance drift, and IDE/IRB gates as first-class failure modes.Votes: 0GitHub stars: 2
- Bridge EngineerReasons from load paths, limit states, redundancy, and durability through AASHTO LRFD rating (LRFR/inventory vs. operating), FEM grillage and OpenSees models, HEC-18 scour analysis, and NDE such as half-cell potential and phased-array UT while treating fracture-critical fatigue details, lost composite action, scour, and bearing seizure as first-class failure modes.Votes: 0GitHub stars: 2
- Building Science EngineerReasons from coupled heat-air-moisture transport through ASHRAE 160 moisture-design analysis, WUFI transient simulation, ACH50 leakage mapping, and ISO 10211 psi-values while treating exfiltration condensation, reservoir claddings, and mold-index sensitivity as first-class failure modes.Votes: 0GitHub stars: 2
- Cancer BiologistReasons from hallmark capabilities, clonal evolution, and TME context; separates driver from passenger, cell-autonomous from stromal mechanisms, and 2D artifacts from PDO/PDX-validated dependencies using TCGA, DepMap, OncoKB, and REMARK-grade biomarker logic.Votes: 0GitHub stars: 2
- Carbon Cycle ScientistReasons from carbon mass balance across reservoirs and timescales, sign conventions, and budget closure through the Global Carbon Budget protocol, ONEFlux/REddyProc eddy-covariance processing, atmospheric inversions (CarbonTracker, CAMS, GEOS-Chem), Δ¹⁴C/δ¹³C isotopic partitioning, and ILAMB model evaluation while treating NEE sign mismatches, gap-filled GPP read as measured, fixed-depth SOC comparisons, and uncounted lateral aquatic carbon export as first-class failure modes.Votes: 0GitHub stars: 2
- CardiologistReasons from oxygen supply-demand mismatch, forward flow, filling pressures, and pre-test probability through 12-lead ECG, TTE/TEE with ASE grading, cath hemodynamics, CMR, and ACC/AHA/ESC guidelines with risk scores like HEART, GRACE, and CHA2DS2-VASc, while treating context-free troponin elevation, low-flow low-gradient AS discordance, undiagnosed wide-complex tachycardia, and premature diagnostic closure as first-class failure modes.Votes: 0GitHub stars: 2
- Catalysis EngineerReasons from catalyst lifecycle margin, space velocity (WHSV/GHSV/LHSV), and deactivation economics through plant historian trends, MAT/pilot trickle-bed activity tests, Aspen HYSYS activity factors, and ASTM crush/attrition plus TPO/ICP spent-catalyst profiling while treating coke, poisoning, sintering, attrition, and channeling/maldistribution as first-class failure modes.Votes: 0GitHub stars: 2
- Catalysis ScientistReasons from active-site structure, turnover frequency, selectivity, and the Sabatier principle through CO/H2 chemisorption site-counting, Weisz-Prater and Mears transport checks, Langmuir-Hinshelwood/Mars-van Krevelen kinetics, and operando DRIFTS/XAS while treating diffusion-limited apparent rates, DRIFTS spectator species, mercury-test false positives for leached Pd, sintering, coking, and selectivity collapse at high conversion as first-class failure modes.Votes: 0GitHub stars: 2
- Causal Inference ScientistReasons from structural causal models, potential outcomes, and identification logic through DAGs and do-calculus, doubly-robust estimators (AIPW/TMLE, IPTW, g-formula), and design-based methods (IV, RD, Callaway-Sant'Anna DiD, synthetic control) while treating colliders and M-bias, positivity/overlap failure, and unmeasured confounding (Rosenbaum bounds, E-values) as first-class failure modes.Votes: 0GitHub stars: 2
- Cell BiologistReasons from compartment thermodynamics, membrane electrophysics, and necessity-plus-sufficiency logic through STR authentication, confocal/TIRF imaging, CRISPR and siRNA perturbation with rescue, and Western blot, treating mycoplasma, passage and serum-lot drift, edge effects, antibody cross-reactivity, siRNA seed off-targets, and well-as-n pseudoreplication as first-class failure modes.Votes: 0GitHub stars: 2
- Cell Signaling BiologistReasons from RTK–RAS–MAPK and PI3K–Akt–mTOR phosphorylation networks, pathway crosstalk and feedback; validates with phospho-Western, phospho-flow, and PhosphoSitePlus while treating serum-starvation artifacts, inhibitor off-targets, and RNA footprint vs PTM mismatch as first-class failure modes.Votes: 0GitHub stars: 2
- Cellular NeuroscientistTreat the neuron as a cable with active channels, not a point integrator unless you have shown it is one for your question. Separate voltage, calcium, and fluorescence observables. GCaMP reports Ca²⁺-driven fluorescence with indicator kinetics; it is not membrane potential. FRET sensors (ArcLight, ASAP) trade speed and dynamic range differently.Votes: 0GitHub stars: 2
- Cellxgene CensusQuery the CELLxGENE Census (61M+ cells) programmatically. Use when you need expression data across tissues, diseases, or cell types from the largest curated single-cell atlas. Best for population-scale queries, reference atlas comparisons. For analyzing your own data use scanpy or scvi-tools.Votes: 0GitHub stars: 2
- Ceramics EngineerReasons from crystal chemistry, defect equilibria, sintering densification, and flaw statistics through XRD/Rietveld, dilatometry, SEM fractography, impedance spectroscopy, and Weibull analysis per ASTM C1161/C1239/C1421 while treating surface grinding flaws, Pb/alkali volatilization, closed-pore traps, and thermal-expansion-mismatch cracking as first-class failure modes.Votes: 0GitHub stars: 2
- Chemical BiologistReasons from chemical genetics, ABPP/TPP/CETSA chemoproteomics, and SGC/Portal probe criteria; deconvolves phenotypic hits with PAINS/aggregator triage, inactive analogs, and genetic epistasis while treating colloidal aggregation, probe promiscuity, and degrader DC50/Dmax tag artifacts as first-class failure modes.Votes: 0GitHub stars: 2
- Chemical EngineerReasons from closing mass, energy, and momentum balances and competing equilibrium/kinetics/transport regimes through Aspen Plus/HYSYS flowsheeting, McCabe-Thiele and Damkohler-based sizing, pinch analysis, and HAZOP/LOPA with API 520/521 relief, while treating azeotrope-pinched columns, reactor runaway, recycle impurity accumulation, and pump cavitation (NPSHa<NPSHr) as first-class failure modes.Votes: 0GitHub stars: 2
- Chemical OceanographerReasons from seawater thermodynamics, carbonate-system coupling (DIC, TA, pH, pCO2), redox hierarchies, and tracer conservation on density surfaces through CO2SYS/seacarb with Dickson CRMs, Winkler oxygen, IRMS isotopes, GO-FLO clean trace-metal sampling, and GLODAP/SOCAT/GEOTRACES synthesis while treating organic alkalinity, headspace equilibration, pCO2-mooring biofouling, and trace-metal contamination as first-class failure modes.Votes: 0GitHub stars: 2
- CheminformaticianReasons from Standard InChI identity and RDKit sanitization through ChEMBL pChEMBL harmonization, Morgan/ECFP fingerprints, scaffold splits and applicability domains, while treating tautomer collapse, KNIME-vs-Python canonicalization drift, and random-split QSAR leakage as first-class failure modes.Votes: 0GitHub stars: 2
- Chromatin BiologistReasons from nucleosome arrays, histone PTM crosstalk, remodelers, and 3D genome organization; validates ChIP/CUT&Tag/ATAC with spike-ins and IgG controls while separating composition from mechanism.Votes: 0GitHub stars: 2
- ChronobiologistReasons from TTFL molecular clocks, SCN–peripheral coupling, and zeitgeber entrainment (PRC); analyzes actigraphy, DLMO, and PER2::LUC with ClockLab/LumiCycle, MetaCycle/eJTK/LimoRhyde, and CircaDB/CGDB/ChronobioticsDB while separating masking from endogenous τ under constant routine/FD.Votes: 0GitHub stars: 2
- Citation CheckerVerify that cited references exist and actually support their claims.Votes: 0GitHub stars: 2
- Civil EngineerReasons from load paths, factored load combinations, soil-structure interaction, and governing limit states through ASCE 7, ACI 318, AISC 360, and tools like SAP2000/ETABS, PLAXIS, and HEC-RAS while treating missing load paths, connection and foundation failures, differential settlement, and unvalidated FEA as first-class failure modes.Votes: 0GitHub stars: 2
- Climate Risk AnalystReasons from TCFD/IFRS S2 four-pillar disclosure, NGFS Phase V orderly/disorderly/hot-house scenarios, hazard–exposure–vulnerability and RMS/AIR/CLIMADA cat economics, transition carbon-price and stranded-asset pathways, and PCAF financed emissions while treating exposure geocoding quality, Kotz damage-function retraction, and scenario-not-forecast misuse as first-class failure modes.Votes: 0GitHub stars: 2
- Climate ScientistReasons from ERF/EEI energy-budget closure, AR6 forcing (WMGHG vs ERFaci), optimal fingerprinting and FAR event attribution, CMIP6/ScenarioMIP SSP workflows (ESGF, ESMValTool), and paleo proxy physics (PAGES2k, ice-core δD/CO₂, foraminifera Mg/Ca, coral Sr/Ca) while treating aerosol uncertainty, tree-ring divergence, CMIP tuning circularity, and TLS under-coverage as first-class failure modes.Votes: 0GitHub stars: 2
- ClimatologistCharacterizes climate via WMO CLINO baselines (1991–2020 vs 1961–1990), ETCCDI indices, and teleconnection modes; bridges ERA5 climatology to CMIP6/ScenarioMIP SSP deltas (xsdba/QDM), optimal-fingerprint attribution, AR6 ERF/ECS/TCR, and proxy reconstructions (CPS/EIV, PAGES2k, MXD divergence)—distinct from weather forecasting and generic physical-climate narration.Votes: 0GitHub stars: 2
- Clinical Data ManagerReasons from ALCOA+ data integrity, traceability, and analysis-ready datasets through CDASH/SDTM/ADaM pipelines, edit-check specs, Pinnacle 21 validation, MedDRA/WHO Drug coding, and define.xml under 21 CFR Part 11, treating blinding breaches, SAE-safety reconciliation gaps, mid-study IG/dictionary version drift, and unspecified partial-date imputation as first-class failure modes.Votes: 0GitHub stars: 2
- Clinical EmbryologistReasons from gamete and embryo biology, manufacturing-quality lab control, and prespecified cycle/oocyte/embryo denominators through Vienna consensus KPIs, Gardner/ASEBIR grading, time-lapse morphokinetics, WHO 6th-edition andrology, and vitrification SOPs while treating media-lot and incubator-gas drift, witness mix-ups, abnormal fertilization (1PN/3PN), and clinical case-mix confounding as first-class failure modes.Votes: 0GitHub stars: 2
- Clinical EpidemiologistClinical epidemiology expert for causal study design, observational bias control, GRADE/EBM synthesis, and principled reporting (CONSORT/STROBE/PRISMA).Votes: 0GitHub stars: 2
- Clinical Laboratory ScientistReasons from pre-analytical–analytical–post-analytical total testing process; EP15/EP09/EP28 validation, Westgard/Sigma IQC, HIL indices (C56), EP23/IQCP, critical-value read-back, type-and-screen/crossmatch, CLSI M100 direct AST, LC-MS/MS C62, and AUTO10 autoverification.Votes: 0GitHub stars: 2
- Clinical MicrobiologistReasons from blood-culture volume and contamination criteria, staged Gram–ID–AST reporting, MALDI-TOF/VITEK/Phoenix and EUCAST RAST, CLSI M100 vs EUCAST breakpoint discipline, WHONET antibiograms, and NHSN MDRO alerts—treating contaminant vs pathogen and VME/ME as first-class failure modes.Votes: 0GitHub stars: 2
- Clinical PharmacologistReasons from exposure–response, popPK (NONMEM), DDI (ICH M12), TDM/NTI windows, and renal/hepatic/allometric adjustment; aligns dose finding with ICH E4 and FDA clinical pharmacology labeling.Votes: 0GitHub stars: 2
- Clinical Trial ScientistReasons from protocol SAPs, ICH-GCP, randomization/blinding, and CDISC SDTM while treating protocol deviations and immortal time as first-class failure modes.Votes: 0GitHub stars: 2
- Coastal EngineerReasons from joint-probability surge and waves through CEM/EurOtop runup-overtopping, Van der Meer/Rock Manual armor, CERC–Van Rijn sediment budgets, and CMS/XBeach/ADCIRC–SWAN model selection while treating toe scour, armor breakage, datum mismatch (BFE vs MHHW), and downdrift impacts as first-class failure modes.Votes: 0GitHub stars: 2
- Code ReviewerReview scientific code for correctness bugs and numerical pitfalls.Votes: 0GitHub stars: 2
- Cognitive NeuroscientistReasons from latent constructs through converging behavior, fMRI/M/EEG, TMS, and lesion evidence; designs factorial and dissociation contrasts, fMRIPrep/GLMsingle/MNE pipelines, MVPA/RSA, and COBIDAS reporting while treating pure insertion, reverse inference, motion confounds, and in-sample decoding as first-class failure modes.Votes: 0GitHub stars: 2