Claude Skills by NVlabs

Build lean, opinionated products using the 37signals philosophy from "Getting Real", "Rework", and "Shape Up". Use when the user mentions "Getting Real", "Rework", "Shape Up", "37signals", "Basecamp method", "six-week cycles", "fixed time variable scope", "appetite vs estimates", "betting table", "breadboarding", "fat marker sketch", "build less", "underdo the competition", "opinionated software", "we have too many meetings", "how do we ship faster", or "stop overbuilding". Also trigger when ...

Calculate A/B test statistical significance. Use when: determining if test results are significant; calculating required sample size; estimating test duration; analyzing conversion experiments; making data-driven decisions

Use when testing skills, commands, or agents for quality. Use after creating new skills, before deploying agents, or when debugging inconsistent agent behavior. Triggers on "evaluate", "test quality", "is this skill working", or QA of AI workflows.

Employee agent lifecycle management system. Use when working with agents/ directory employee agents - starting, stopping, monitoring, or assigning tasks to Dev/QA agents running in tmux sessions. Completely independent of CAO, uses only tmux + Python.

Audit local AI coding-agent sessions with agenttrace. Use when the user asks to inspect Claude Code, Codex CLI, Gemini CLI, Qwen Code, Cline, Aider, Cursor exports, Hermes Agent, OpenCode, OpenClaw, Pi, Oh My Pi, Kimi CLI, Copilot-style logs, or generic JSON/JSONL traces for cost, tokens, tool failures, latency, anomalies, health, diffs, or CI gates.

Use when analyzing server logs to understand how AI crawlers (GPTBot, ClaudeBot, PerplexityBot) interact with your site. Use when optimizing content placement for LLM retrieval, diagnosing why AI search isn't citing your content, or auditing crawl patterns to find optimization gaps.

Générez des prompts optimisés pour chaque modèle de génération vidéo IA (Veo 3, Runway Gen-3, Kling 2.6, Pika), en exploitant leurs forces spécifiques. Use when: **Animer des frames de storyboard** - Transformer des images fixes en vidéo; **Choisir le bon modèle** - Sélectionner Veo, Runway, Kling ou Pika selon le besoin; **Optimiser la qualité de génération** - Prompts structurés pour meilleurs résultats; **Créer des transitions fluides** - Scene extension, first/last frame; **Utiliser le mo...

Validez la qualité de vos vidéos IA avant publication avec une checklist complète couvrant technique, créatif, et positionnement marque. Use when: **Avant publication** - Dernière validation avant mise en ligne; **Revue client** - Préparer les points de feedback anticipés; **Itération qualité** - Identifier les problèmes à corriger; **Go/No-Go decision** - Décider si la vidéo est prête; **Post-mortem** - Analyser pourquoi une vidéo a (ou n'a pas) performé

Business Analyst Skill. Triggered when users ask about business analysis, industry research, competitive analysis, product analysis, business model analysis, business opportunity discovery, market entry strategy, investment decisions, strategic planning, due diligence, and other strategic topics. Delivers in-depth, decision-grade HTML research reports through a seven-stage workflow (Briefing → Framing → Planning → Research → Insights → Report → Iteration).

Prepares academic career documents and professional-development materials for faculty and researchers. Use when drafting academic CVs, research statements, teaching philosophies, diversity statements, faculty-position cover letters, tenure dossiers, promotion narratives, academic portfolios, or mentorship statements, and when planning conference-networking strategy, building academic web presence, setting up ORCID profiles, or understanding impact metrics. Part of the AlterLab Academic Skills...

Runs time series machine learning with the aeon library — classification, regression, clustering, forecasting, anomaly detection, segmentation, and similarity search via scikit-learn compatible APIs. Use when working with temporal data, sequential patterns, or time-indexed observations (univariate or multivariate) that need specialized algorithms beyond standard ML approaches. Part of the AlterLab Academic Skills suite.

Access the AlphaFold DB of 200M+ AI-PREDICTED protein structures — retrieve models by UniProt accession, download PDB/mmCIF files, and analyze prediction confidence metrics (pLDDT, PAE). Use when a UniProt ID needs a computationally predicted 3D structure or when no experimental structure exists, for homology modeling, protein engineering, or structure-based drug discovery; for EXPERIMENTALLY determined structures (X-ray, cryo-EM, NMR) prefer alterlab-pdb, and for protein sequences, annotatio...

Build, slice, concatenate, read, and write AnnData annotated data matrices (obs, var, X, layers, obsm, uns) — the scverse data STRUCTURE, not an analysis pipeline. Use when creating or wrangling .h5ad/zarr files, managing cell and gene annotations, concatenating batches, or handling layers/obsm/backed-mode; for the QC, normalization, clustering, UMAP, and differential-expression analysis pipeline prefer alterlab-scanpy instead, and for RNA velocity from spliced/unspliced layers prefer alterla...

Infer gene regulatory networks (GRNs) from expression matrices using arboreto's scalable GRNBoost2 and GENIE3 tree-ensemble algorithms with Dask-distributed computation. Use when analyzing bulk or single-cell RNA-seq transcriptomics to map transcription-factor-to-target-gene regulatory interactions, build adjacency networks, or run the GRN-inference step of a SCENIC pipeline on large datasets. Part of the AlterLab Academic Skills suite.

Search and retrieve preprints from arXiv via the Atom API by keywords, authors, arXiv IDs, date ranges, or subject categories. Use when finding or fetching papers in physics, mathematics, computer science, quantitative biology, quantitative finance, statistics, electrical engineering, or economics, or resolving an arXiv ID to its metadata and PDF. Part of the AlterLab Academic Skills suite.

Processes astronomy and astrophysics data with the Astropy Python library — celestial coordinates, physical units, FITS files, cosmological calculations, time systems, tables, and world coordinate systems (WCS). Use when tasks involve coordinate transformations, unit conversions, FITS file manipulation, cosmological distance calculations, time scale conversions, or general astronomical data analysis. Part of the AlterLab Academic Skills suite.

Search scientific papers and retrieve structured experimental data extracted from full-text studies via the BGPT MCP server, returning 25+ fields per paper (methods, results, sample sizes, quality scores, conclusions). Use when running a literature review or evidence synthesis, or when needing experimental details (sample sizes, effect sizes, methods, quality scores) that abstracts alone do not provide. Part of the AlterLab Academic Skills suite.

Manipulate biological sequences, parse FASTA/GenBank/PDB files, run phylogenetics, and access NCBI/PubMed programmatically via Biopython (Bio.SeqIO, Bio.Entrez, Bio.PDB, Bio.Blast). Use when scripting custom bioinformatics pipelines, batch-processing sequence files, automating BLAST, or fetching records from Entrez — for quick one-off database lookups use gget, for unified multi-service integration use bioservices. Part of the AlterLab Academic Skills suite.

Search the bioRxiv preprint server and retrieve paper metadata or download PDFs via its API. Use when finding life sciences preprints by keywords, authors, DOI, date ranges, or categories, or when conducting a biology literature review of not-yet-peer-reviewed work. Part of the AlterLab Academic Skills suite.

This skill should be used when the user asks about "animation", "storyboard", "animatic", "pre-visualization", "previz", "character design", "motion planning", "animation storyboard", "act as an animation designer", "animation mode", "character design brief", "animation pipeline", "2D animation", "3D previz", "frame-by-frame", "keyframe planning", "storyboard pro", "toon boom", "animatic timing", "shape language", "turnaround sheet", "motion reference", "animation layout", "previz workflow", ...

This skill should be used when the user asks about "documentary", "documentary research", "interview questions", "documentary treatment", "archival research", "documentary ethics", "act as a documentary researcher", "documentary mode", "non-fiction film", "documentary proposal", "documentary subject research", "oral history", "verite", "observational documentary", or needs expertise in documentary research methodology, interview preparation, treatment writing, and ethical frameworks for non-f...

This skill should be used when the user asks about "film festival", "festival submission", "logline", "synopsis writing", "director's statement", "festival strategy", "act as a festival strategist", "festival mode", "film submission", "short film festival", "festival circuit", "premiere strategy", "FilmFreeway", "Withoutabox", "press kit for film", or needs expertise in festival submission materials, loglines, synopses, director statements, and festival circuit planning. Part of the AlterLab ...

This skill should be used when the user asks about "film analysis", "movie analysis", "film essay", "sequence analysis", "mise-en-scene", "film theory", "cinematography analysis", "film critique", "act as a film analyst", "film analysis mode", "formal analysis", "auteur theory", "film semiotics", "narrative analysis film", "film studies essay", "film review vs analysis", "close reading film", "shot-by-shot analysis", "annotated film bibliography", "film criticism", or needs expertise in acade...

This skill should be used when the user asks about "film pitch", "treatment writing", "pitch deck", "lookbook", "mood board", "film proposal", "funding application", "act as a film pitch developer", "film pitch mode", "pitch package", "film financing", "producer pitch", "story treatment", "concept development", "film grant application", or needs expertise in film treatments, pitch packages, lookbooks, mood boards, and funding proposals for film projects. Part of the AlterLab FC Skills collect...

This skill should be used when the user asks about "post-production", "video editing", "color grading", "color correction", "sound post-production", "DaVinci Resolve", "Premiere Pro", "editing workflow", "act as a post-production guide", "post-production mode", "export settings", "delivery specs", "editing strategy", "rough cut", "final cut", "LUT", "audio mixing", or needs expertise in editing strategy, color grading, sound post-production, NLE workflows, and delivery specifications. Part of...

This skill should be used when the user asks about "pre-production", "shot list", "storyboard", "shooting schedule", "call sheet", "script breakdown", "scene breakdown", "production planning", "act as a pre-production planner", "pre-production mode", "location scouting", "crew planning", "shooting day schedule", "camera setup list", or needs expertise in pre-production planning, shot design, script breakdowns, and shooting logistics. Part of the AlterLab FC Skills collection (Cinema & Digital...

This skill should be used when the user asks about "production management", "film budget", "scheduling", "crew management", "location logistics", "risk assessment", "act as a production manager", "production manager mode", "line producing", "production budget", "crew roles", "film insurance", "production timeline", "location permit", "production paperwork", or needs expertise in film budgets, production scheduling, crew management, location logistics, and risk mitigation for film projects. Pa...

This skill should be used when the user asks about "screenwriting", "screenplay", "script writing", "dialogue writing", "film script", "short film script", "scene writing", "act as a screenwriter", "screenwriter mode", "screenplay format", "story structure", "character development for film", "three-act structure", "script formatting", "write a scene", "screenplay outline", or needs expertise in screenplay development, dialogue craft, dramatic structure, and professional script formatting. Par...

This skill should be used when the user asks about "sound design", "foley", "film sound", "sound effects", "audio post-production", "spatial audio", "sound mixing", "act as a sound designer", "sound design mode", "Dolby Atmos", "ambience design", "sound map", "music supervision", "dialogue editing", "sound for film", "surround sound", or needs expertise in sound design planning, foley workflows, music supervision, spatial audio, and mixing strategies for film. Part of the AlterLab FC Skills c...

This skill should be used when the user asks about "subtitles", "subtitling", "SRT file", "VTT file", "subtitle timing", "translation for film", "localization", "closed captions", "SDH", "act as a subtitle expert", "subtitle mode", "subtitle formatting", "subtitle translation", "accessibility captions", "subtitle synchronization", "burned-in subtitles", or needs expertise in SRT/VTT creation, subtitle timing, translation adaptation, and accessibility for film and video. Part of the AlterLab F...

This skill should be used when the user asks about "VFX", "visual effects", "compositing", "green screen", "chroma key", "After Effects", "Nuke", "CGI", "motion tracking", "rotoscoping", "act as a VFX supervisor", "VFX mode", "visual effects pipeline", "matte painting", "particle effects", "3D integration", "VFX breakdown", or needs expertise in compositing workflows, visual effects planning, Nuke/After Effects pipelines, and CGI integration. Part of the AlterLab FC Skills collection (Cinema ...

Query the CZ CELLxGENE Census (61M+ cells) programmatically via cellxgene-census and TileDB-SOMA, slicing expression by tissue, disease, or cell type and returning AnnData. Use when pulling reference single-cell RNA-seq data from the largest curated public atlas, running population-scale queries, or benchmarking your data against a reference — for analyzing your own dataset use scanpy or scvi-tools. Part of the AlterLab Academic Skills suite.

Query ChEMBL via the chembl_webresource_client Python client for curated bioactive molecules and drug-like compound libraries at scale — search compounds by structure or physicochemical properties, retrieve bioactivity measurements (IC50, Ki, EC50), and find inhibitors of a target. Use when screening chemical libraries, mining curated bioactivity for a protein, running SAR studies, or sourcing medicinal-chemistry data; for measured protein-ligand binding affinities (Ki/Kd/IC50) prefer alterla...

Builds, simulates, and runs quantum circuits with Cirq, Google Quantum AI's framework for NISQ hardware, noise-aware low-level circuit design, and noise characterization. Use when targeting Google Quantum AI processors (Sycamore/Weber), designing noise-aware NISQ circuits, or running characterization experiments (randomized benchmarking, XEB). For IBM Quantum hardware and Qiskit Runtime prefer alterlab-qiskit; for gradient-trained quantum ML and hybrid quantum-classical models prefer alterlab...

Manages citations for academic research — searches Google Scholar and PubMed for papers, extracts accurate metadata, validates citations, and generates properly formatted BibTeX entries. Use when finding papers, verifying citation information, converting DOIs to BibTeX, checking reference accuracy in scientific writing, or building a bibliography. Part of the AlterLab Academic Skills suite.

Query ClinicalTrials.gov via its API v2 to search trials by condition, drug, location, recruitment status, or phase and retrieve trial details by NCT ID. Use when finding interventional or observational studies, checking trial status and eligibility for patient matching, or exporting clinical trial records for research. Part of the AlterLab Academic Skills suite.

Access ClinPGx pharmacogenomics data (the successor to PharmGKB) to query gene-drug interactions, CPIC/DPWG dosing guidelines, drug labels, and pharmacogene records. Use when interpreting pharmacogenes (CYP2D6, CYP2C19, TPMT, DPYD, SLCO1B1), looking up genotype-guided drug dosing, checking PGx drug-safety associations (e.g. HLA-B*57:01 and abacavir), or supporting precision medicine and clinical pharmacogenomics decisions. For star-allele definitions/frequencies see PharmVar; for germline/som...

Query NCBI ClinVar via the E-utilities API or FTP for the clinical significance (pathogenicity) of human germline genetic variants, searching by gene, variant, condition, or genomic position and interpreting ACMG/AMP classifications and review-status star ratings. Use when assessing whether a variant is pathogenic, likely pathogenic, VUS, likely benign, or benign, resolving conflicting interpretations, or annotating a VCF with ClinVar clinical significance. For population allele frequencies b...

Scales pandas/NumPy workflows beyond memory with Dask distributed computing — parallel DataFrames, arrays, delayed task graphs, and cluster execution. Use when existing pandas/NumPy code must run on larger-than-RAM data or across clusters, for parallel file processing, distributed ML, or integration with existing pandas code. For out-of-core analytics on a single machine prefer vaex; for in-memory speed prefer polars. Part of the AlterLab Academic Skills suite.

Wraps RDKit in a high-level, pandas-friendly datamol interface with sensible defaults for everyday drug discovery — SMILES/SDF loading into DataFrames, molecule standardization, descriptors, fingerprints, Butina clustering, 3D conformer generation, scaffold analysis, and parallel batch processing, returning native rdkit.Chem.Mol objects. Use when running standard cheminformatics pipelines on molecule tables with minimal boilerplate; for low-level control, custom sanitization, or specialized a...

Runs molecular machine learning with DeepChem — diverse featurizers, pre-built MoleculeNet benchmark datasets, and pre-trained models (ChemBERTa, GROVER) for property prediction (ADMET, toxicity, solubility) via traditional ML or graph neural networks. Use when running end-to-end molecular ML experiments that need MoleculeNet benchmarks, scaffold splitting, or ready-made models with minimal setup; for building custom PyTorch graph architectures prefer alterlab-torchdrug, and for standalone mo...

Process and visualize deep-sequencing coverage with the deepTools CLI — convert BAM to bigWig (bamCoverage), build log2 ratio tracks (bamCompare), run QC (multiBamSummary correlation, PCA, plotFingerprint), apply the ATAC-seq Tn5 shift (alignmentSieve --ATACshift), and make TSS/peak heatmaps and profiles (computeMatrix, plotHeatmap, plotProfile). Use for coverage tracks, signal heatmaps/profiles, normalization (RPGC/CPM/RPKM), and effective-genome-size lookups for ChIP-seq, ATAC-seq, MNase-se...

Applies computational methods to humanities research — text mining and NLP (LDA/BERTopic topic modeling, sentiment, named entity recognition with spaCy/NLTK), corpus linguistics (concordance, collocation, keyness), digital archives (Dublin Core, TEI XML), GIS for history, network analysis, stylometry and authorship attribution, OCR (Tesseract, Kraken, Transkribus), and data visualization (Gephi, Palladio). Use when distant-reading a literary corpus, mapping historical events or trade networks...

Exploratory data analysis (EDA) on a scientific data file — auto-detects the format, runs structure/quality/statistics checks, and writes a markdown EDA report with downstream recommendations. Use when asked to "explore", "analyze", "summarize", "profile", or "QC" a data file, or to understand its structure/content/quality before deciding what analysis to run. Covers tabular (.csv .tsv .xlsx .parquet), arrays (.npy .npz .hdf5 .h5 .mat .fits), sequence/genomics (.fasta .fastq .sam .bam .vcf .b...

Accesses, analyzes, and extracts data from SEC EDGAR filings using the edgartools Python library. Use when working with SEC filings, financial statements (income statement, balance sheet, cash flow), XBRL financial data, insider trading (Form 4), institutional holdings (13F), company financials, annual/quarterly reports (10-K, 10-Q), proxy statements (DEF 14A), 8-K current events, company screening by ticker/CIK/industry, multi-period financial analysis, or any SEC regulatory filings. Part of...

Access the European Nucleotide Archive (ENA) via its API and FTP to retrieve DNA/RNA sequences, raw sequencing reads (FASTQ), and genome assemblies by accession, with support for multiple formats. Use when downloading reads or sequences for a study, run, or sample accession, or when sourcing nucleotide data for genomics and bioinformatics pipelines. Part of the AlterLab Academic Skills suite.

Query the Ensembl genome database REST API across 250+ species for gene lookups, sequence retrieval, variant analysis, comparative genomics, orthologs, and Variant Effect Predictor (VEP) annotations. Use when mapping gene IDs or coordinates, fetching genomic sequence, finding orthologs across species, or predicting variant consequences for genomic research. Part of the AlterLab Academic Skills suite.

Run ESM protein language models — ESM3 for generative multimodal protein design across sequence, structure, and function, and ESM C for efficient embeddings and representations — locally or via the cloud Forge API. Use when working with protein sequences, structures, or function prediction, designing novel proteins, generating protein embeddings, performing inverse folding, or doing protein-engineering tasks. Part of the AlterLab Academic Skills suite.

Parse and write FCS (Flow Cytometry Standard) files v2.0-3.1 with FlowIO — extract event data as NumPy arrays, read $-keyword metadata and channel/parameter definitions, and convert events to CSV or pandas DataFrame. Use when loading raw .fcs flow-cytometry files, inspecting channels and metadata, or preprocessing cytometry data for downstream gating and analysis. Part of the AlterLab Academic Skills suite.

This skill should be used when the user asks about "camera moves", "AI camera presets", "dolly", "crane shot", "orbit shot", "crash zoom", "bullet time", "360 orbit", "FPV arc", "pan", "tilt", "dutch angle", "tracking shot", "Higgsfield camera", "Cinema Studio", "camera direction", "cinematic grammar", "Sora 2 Presets", "Higgsfield Assist", "Soul Cast", "content scoring", "act as a camera director", "camera director mode", "camera language", "lens selection", "focal length", "21:9 cinematic",...