Use this skill to traverse the official Reactome pathway hierarchy and summarize the ancestor chain, direct children, and descendant count for a target stable ID.
Scanned 9/8/2026
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npx -y skills add ma-compbio-lab/SkillFoundry --skill reactome-pathway-hierarchy-walk-starter --agent claude-codeInstalls into .claude/skills of the current project.
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# Reactome Pathway Hierarchy Walk Starter
Use this skill to traverse the official Reactome pathway hierarchy and summarize the ancestor chain, direct children, and descendant count for a target stable ID.
## What it does
- Fetches the official Reactome `eventsHierarchy` tree for a species.
- Locates a target pathway or reaction stable ID inside the nested hierarchy.
- Exports a compact JSON summary with the ancestor path and subtree shape.
## When to use it
- You need a verified starter for `pathway traversal and hierarchy walks`.
- You want a lightweight way to place a Reactome stable ID inside its broader biological context.
- You need deterministic JSON for tests, demos, or downstream routing logic.
## Example
```bash
python3 skills/systems-biology/reactome-pathway-hierarchy-walk-starter/scripts/run_reactome_hierarchy_walk.py \
--species 9606 \
--stable-id R-HSA-141409 \
--out scratch/reactome-hierarchy/r_hsa_141409_hierarchy.json
```
## Verification
- Skill-local tests: `python3 -m unittest discover -s skills/systems-biology/reactome-pathway-hierarchy-walk-starter/tests -p 'test_*.py'`
- Expected summary: `top_level_pathway == "Cell Cycle"` and `ancestor_count == 5` for `R-HSA-141409`
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