Research

Expert-thinking profile for Precision Medicine Scientist (clinical / research): Reasons from molecular profiles, tiered actionability, tumor purity, and clonal architecture through OncoKB and AMP/ASCO/CAP tiers, Mutect2/STAR-Fusion calling, IGV review, and CPIC pharmacogenomic guidelines while treating FFPE C-to-T deamination, CHIP mimicking somatic drivers, immortal-time bias in real-world data...

Runs a pre-submission review of a technical paper across five dimensions: macro logic, writing details, English grammar, LaTeX formatting, and figure quality. Uses a reviewer-style severity taxonomy (CRITICAL / MAJOR / MINOR) and flags banned AI-tone vocabulary and em-dash misuse. Use when the user asks to 'review this paper', 'audit before submission', 'check the draft', 'find issues', 'proofread', or within one week of a submission deadline.

Create research posters using HTML/CSS that can be exported to PDF or PPTX. Use this skill ONLY when the user explicitly requests PowerPoint/PPTX poster format. For standard research posters, use latex-posters instead. This skill provides modern web-based poster design with responsive layouts and easy visual integration.

Analyze product data and manage product tooling in PostHog. Use when the user wants product analytics or insights, HogQL/SQL queries, feature flags, experiments and A/B tests, error tracking, session replay, surveys, LLM analytics, dashboards, data warehouse, or PostHog documentation.

Expert-thinking profile for Polymer Scientist (synthesis / characterization / rheology-morphology / polymer processing / failure analysis): Reasons from molecular weight distribution, Tg/Tm and crystallinity, viscoelasticity, and phase behavior through GPC/SEC, DSC heat-cool-heat, capillary and oscillatory rheology, WAXD/SAXS, and DMA while treating thermal-history erasure, moisture hydrolysis, incomplete cure, and wrong-grade-lot artifacts as first-class...

Expert-thinking profile for Polymer Chemist (wet-lab / synthetic polymer chemistry): Designs and interprets polymer synthesis, characterization, and structure–property relationships from mechanism (chain-growth, step-growth, RDRP, ROMP) through absolute MW verification to application-relevant thermal and rheological data.

Expert-thinking profile for Plant Physiologist (wet-lab / greenhouse / field plant physiology): Reasons from source–sink carbon–water balance, FvCB A–Ci and Ball–Berry gs models, LI-COR/PAM gas exchange, Scholander Ψ, drought–salt–heat signaling, and MIAPPE/Phytozome workflows while treating chamber leakage, pot-bound roots, and Fv/Fm–yield conflation as first-class failure modes.

Expert-thinking profile for Plant Pathologist (diagnostic clinic / field epidemiology / wet-lab & molecular phytopathology): Reasons from the disease triangle, sign vs. symptom, and trophic strategy (biotroph/necrotroph/hemibiotroph); runs clinic-to-Koch workflows (TWA isolation, Phytophthora pear baiting, Baermann nematodes, EPPO PM7/qPCR with matrix-specific Ct cutoffs) and epidemic analysis (AUDPC/AUDPS, Vanderplank parameters, GLMMs)...

Expert-thinking profile for Planetary Scientist (solar-system / remote-sensing & in situ / exoplanet detection-characterization / mission archives (PDS, SPICE)): Expert profile for planetary scientist — see AGENTS.md for field-specific methods and failure modes.

Expert-thinking profile for Physician-Scientist (clinical / translational / basic and patient-oriented research): Reasons across the bedside–bench cycle and T0–T4 spectrum; navigates PSTP/ABIM pathways, K08/K23/R01 funding, IRB/IND/IDE sponsor-investigator duties, and CONSORT/SPIRIT reporting while treating protected-time loss and preclinical irreproducibility as first-class failure modes.

Expert-thinking profile for Physical Oceanographer (observational / field / computational ocean physics): Reasons from geostrophy, thermal wind, PV, and Ekman/Sverdrup balances; integrates GO-SHIP/CCHDO sections, Argo DMQC, DUACS/CMEMS altimetry, and ROMS/MITgcm/NEMO validation while treating reference-level transport ambiguity, Argo conductivity drift, and MDT/alias artifacts as first-class failure modes.

Expert-thinking profile for Physical Chemist (wet-lab / calorimetry (DSC, ITC) / spectroscopy (FTIR, Raman, UV-vis) / kinetics / statistical thermodynamics): Reasons from state functions, partition functions, rate laws, and selection rules through Eyring and van't Hoff fits, DSC/ITC calorimetry, and stopped-flow spectroscopy anchored to NIST thermochemical data, while treating inner-filter and aggregation artifacts, curved Arrhenius plots from mechanism change, and...

Expert-thinking profile for Phylogeneticist (computational / molecular & morphological systematics): Reasons from Hennigian homology and MSC/coalescent-aware species trees through MAFFT/trimAl alignment, IQ-TREE 3 ModelFinder and gCF/sCF/gDF discordance, ASTRAL/ASTRAL-Pro 2/BEAST2 FBD dating, bPP/BFD* delimitation, and MIAPA/TreeBASE provenance while treating LBA, mis-rooting, compositional heterogeneity, gene flow...

Expert-thinking profile for Photovoltaics / Solar Cell Scientist (device characterization / loss-budget analysis / c-Si & perovskite tandem / module reliability (IEC 61215/61730)): Reasons from the Shockley-Queisser detailed-balance limit and the diode coupling of Voc, Jsc, FF, and Rs/Rsh through light I-V, Suns-Voc implied Voc, EQE integration, lifetime mapping (QSSPC, μ-PCD, DLTS), and IEC 60904/61215 qualification while treating spectral mismatch, surface-recombination and shunt losses...

Expert-thinking profile for Photonics Scientist (research / integrated photonics / nonlinear optics): Reasons from guided-wave dispersion, ring FSR–Q–coupling, and FWM phase matching; designs waveguides, lasers, and modulators with Lumerical MODE/FDTD/CHARGE/INTERCONNECT while treating dispersive FSR mismatch, TPA/FCA/XPM detuning, mesh dispersion, etalon ripples, and thermal bistability as first-class failure modes.

Expert-thinking profile for Photochemist (photophysics / excited-state spectroscopy / actinometry / time-resolved (TCSPC, flash photolysis) / photoredox & solar chemistry): Reasons from Jablonski diagrams, quantum yields, and excited-state potential energy surfaces through ferrioxalate actinometry, TCSPC and transient-absorption flash photolysis, Stern–Volmer quenching, and TDDFT/CASPT2 calculations while treating inner-filter distortion, oxygen-sensitive triplet pathways...

Expert-thinking profile for Pharmacologist (wet-lab / in vitro pharmacology / drug discovery): Reasons from receptor occupancy, Black–Leff τ, EC50/IC50/Kd/Ki distinctions, Schild/Cheng–Prusoff antagonism, allosteric PAM/NAM cooperativity, GPCR bias, and PK/PD linkage; interprets binding/functional/HTS via GtoPdb/ChEMBL while treating spare receptors, radioligand depletion, and assay autofluorescence as...

Expert-thinking profile for Pharmacokineticist (clinical / research): Reasons from mass balance, exposure-response, and separation of structural from statistical models through NCA in Phoenix WinNonlin, mixed-effects popPK in NONMEM, PBPK in Simcyp/GastroPlus, and VPC diagnostics while treating BLQ mishandling, ETA shrinkage, over-parameterization for small n, and unit/analyte/matrix...

Expert-thinking profile for Phage Biologist (wet-lab / phage isolation, genomics, and phage-therapy R&D): Reasons from lytic vs lysogenic cycles, PFU/MOI/Poisson kinetics, one-step growth and EOP host-range matrices, PhagesDB/Phamerator/Pharokka genomics, and CRISPR/restriction escape—treating prophage immunity, defective particles, and therapy integrase scans as first-class failure modes.

实战 SRC / 众测 / Bug bounty 漏洞挖掘工作流 skill。包含：5 阶段方法论（intake → recon → enum → hunt → report）、19 个攻击类 playbook（SQLi/XSS/RCE/SSRF/IDOR/CSRF/Path Traversal/File Upload/SSTI/XXE/Race/HTTP Smuggling/OAuth/JWT/SAML/GraphQL/Mobile/LLM/DoS）、305 个结构化 payload、263 个 WAF/EDR 绕过变体、2887 份 HackerOne 真实 High/Critical 已披露案例、77,000+ WooYun 案例统计、国产 OA / 中间件指纹库、银行 / 电信行业垂直 playbook。当用户提到 "src 挖洞 / src 漏洞挖掘 / bug bounty / 众测 / hackerone / 漏洞赏金 / SRC / 任意 X 漏洞 / 渗透测试" 或问"如何挖某个目标 / 怎么测某个 API / 如何绕过 WAF" 时触发。

Systematic peer review toolkit. Evaluate methodology, statistics, design, reproducibility, ethics, figure integrity, reporting standards, for manuscript and grant review across disciplines.

Expert-thinking profile for Pedologist (soil survey / pedon morphology / classification (USDA Taxonomy, WRB) / micromorphology / digital soil mapping): Reasons from CLORPT factors, genetic horizons, and catenary position through the USDA Field Book, Soil Taxonomy and WRB 2022 keys, XRD clay mineralogy, micromorphology, and NASIS/SSURGO correlation while treating colluvial-versus-illuvial Bt confusion, lithologic discontinuities, surface-color-alone drainage calls...

Expert-thinking profile for Pavement Engineer (mechanistic-empirical design / flexible & rigid pavements / NDE & forensics / asset management (MEPDG, FWD)): Reasons from layered-elastic stress/strain, traffic spectra, climate, and material temperature- dependence through AASHTOWare Pavement ME (MEPDG) hierarchical inputs, FWD deflection- basin backcalculation with GPR/core thickness, binder PG selection, and LTPP- calibrated transfer functions, while treating mis-specified...

Expert-thinking profile for Pathologist (clinical / research): Reasons from H&E morphology, pretest-probability differentials, and pre-analytic integrity through CAP synoptic protocols, staged IHC and FISH panels, WHO/AJCC grading and staging, and Bethesda/Paris/Milan cytology systems while treating crush artifact, fixation/decalcification failure, single-frozen-section overcall...