Research

Expert-thinking profile for Neuroanatomist (wet-lab histology / tract tracing + computational atlas registration): Stereotaxic targeting and skull leveling, Paxinos/Allen atlases, anterograde/retrograde tracing, Nissl vs IHC, BrainGlobe/QuickNII registration, and injection-spread or fibers-of-passage artifacts.

Expert-thinking profile for Network Scientist (graph theory / community detection / generative models (SBM, ERGM) / network dynamics / null-model inference): Reasons from adjacency structure, generative models, and null hypotheses through configuration- model and SBM/ERGM nulls, CSN power-law fitting with log-normal Vuong tests, and multi-algorithm community detection (Louvain, Leiden, Infomap, graph-tool) while treating artifactual scale-free tails from correlation...

Draft, restructure, or plan Nature-style manuscript sections and initial-submission materials from author-provided claims, results, figures, notes, or Chinese drafts. Use when the user wants to write or rebuild an abstract, introduction, related-work, method, experiments, discussion, conclusion, title, full manuscript argument, pre-submission cover letter, title page, highlights, author-contribution statement, availability/declaration text, reviewer suggestions, or a complete initial submissi...

Simulate a Nature-style reviewer assessment from the referee perspective rather than an author rebuttal. Use when the user wants a pre-submission review, reviewer report, peer-review style critique, novelty/significance/technical soundness assessment, reviewer-style manuscript evaluation, 审稿人视角评估, 预审稿意见, or Nature reviewer report. Return 3 reviewer reports plus a cross-review synthesis, grounded only in the local Nature reviewer source basis. Also trigger on general pre-submission review requ...

Draft, audit, or revise Nature-style revision correspondence packages: point-by-point reviewer response letters, rebuttal letters, revision cover letters, LaTeX cover/response templates, and red-marked revised-manuscript excerpts. Use for reviewer comments, editor decision letters, pasted editorial emails, response drafts, cover letters, response to reviewers, rebuttal, 修回信, 返修邮件, 编辑邮件, 返修 cover letter, 审稿意见回复, 逐点回复, 大修回复, 小修回复, 回复审稿人, 修改稿回复, 写rebuttal, 回应审稿意见, 标红修改, or LaTeX 模板.

Build full-paper Chinese-English side-by-side, figure/table-aware, source-grounded Markdown readers for journal or conference papers from PDF, DOI, arXiv, publisher HTML, or pasted text. Use whenever the user asks to translate or read a paper, make 中英文对照/原文对照/全文翻译解读, extract figures or tables into the right positions, preserve figure/table placement near relevant prose, or keep exact source anchors for every block. This skill must not degrade into a summary-only output unless the user explici...

Build a complete Nature-style Chinese PPTX presentation from a scientific paper, preprint, PDF, article text, figure legends, or reading notes. Use for journal club, group meeting, thesis seminar, paper sharing, conference or defense decks, and Chinese requests such as 论文做PPT、论文汇报、组会PPT、文献汇报、学术汇报、做幻灯片、读书报告PPT. It classifies paper type, builds an evidence-led story, selects key figures, writes Chinese slide content and speaker notes, creates the actual .pptx, and runs corrective QA for complet...

Multi-source literature search, citation verification, strict independent other-citation audits, article-level citation metric tables, influential citer profiling with citation-context extraction, MeSH search strategy, citation file management (.nbib/.ris/.bib conversion), and reference management (BibTeX, related articles, ID conversion) via MCP tools (PubMed, CrossRef, arXiv, Scopus, ScienceDirect). Use for coordinated literature workflows beyond one MCP call, including 文献检索、 查文献、找文献、文献综述检索...

Expert-thinking profile for Natural Products Chemist (wet-lab / isolation & structure elucidation / metabolomics-guided discovery): Reasons from dereplication (GNPS FBMN, NPAtlas, SNAP-MS, COCONUT), bioassay-guided and MS-triggered isolation, NMR/HRMS structure tiers (DP4+/DU8+), antiSMASH/MIBiG BGC linkage, and PAINS/IMP assay interference while treating HMBC ambiguity, stereochemical misassignment, and aggregator false positives as first-class...

Expert-thinking profile for Nanophysicist (experimental / low-T transport / SPM / electron spectroscopy): Reasons from quantum confinement dimensionality, Coulomb diamonds and SET conditions, Kondo vs Luttinger-liquid power laws, and lock-in cryostat transport through STM/STS, AFM/KPFM, and STEM/EELS while treating charging artifacts, tip convolution, contact resistance, and beam-damage plasmon shifts as first-class...

Expert-thinking profile for Nanomaterials Scientist (colloidal synthesis / multi-modal characterization / nanoscale metrology / EHS-regulatory (ISO/TR 13014, OECD)): Reasons from size-dependent thermodynamics, surface-to-volume ratio, and DLVO colloidal stability through TEM/STEM statistics, DLS/NTA, XRD Scherrer, XPS, ICP-MS, and PL quantum-yield methods while treating aggregation, beam damage, intensity-weighted DLS sizing bias, and Ostwald ripening as first-class failure modes.

Expert-thinking profile for Mycologist (field / herbarium / culture & molecular systematics): Reasons from fungal life cycles, voucher-first taxonomy, and integrated sporocarp–culture–ITS/multilocus workflows; uses MycoBank/UNITE/MaarjAM, FUSARIUM-ID, EPPO Q-bank, and MycoCosm while treating rich-media non-sporulation, ITS saturation in Fusarium/Penicillium, AMF SSU vs ITS misuse, environmental-DNA-only names...

Expert-thinking profile for Mycobacteriologist (BSL-3 clinical microbiology / TB-NTM culture & molecular DST / WGS resistance genotyping / public-health reporting): Reasons from slow-growing acid-fast bacilli, knife-edge NALC-NaOH decontamination, and BSL-3 aerosol risk through MGIT culture, Xpert MTB/RIF and line-probe assays, MALDI- TOF and WGS resistance calls against the WHO mutation catalog while treating over- decontamination false negatives, laboratory cross-contamination...

Discover and safely explore Moody's MCP tools. Use when the user wants to see what Moody's data is available, verify MCP connectivity, look up an entity, or run a lightweight ratings/research probe before deeper analysis.

Use when the user asks for Moody's company profiles, ownership, ratings, credit opinions, financial statements, filings, peers, research, or credit-risk analysis for a company.

Expert-thinking profile for Molecular Virologist (wet-lab / reverse genetics & virus–host molecular mechanism): Reasons from Baltimore mRNA pathways, RNP/polymerase biochemistry, cap-snatching and expression strategy, CPER/BAC/trVLP rescue, protease cis/trans mapping, viral-factory LLPS, and CRISPR host-factor screens (Brunello/MAGeCK/replicon/TRPPC) with iCLIP/ChIP-seq—while treating CPER PCR errors, DIP packaging competition...

Expert-thinking profile for Molecular Pathologist (clinical / anatomic & molecular diagnostic pathology): Reasons from tumor cellularity, assay-specific LOD, and AMP/ASCO/CAP Tier I–IV classification; validates IHC (CAP ≥90% concordance), FISH (HER2/ALK break-apart), and NGS oncology panels under CAP/CLIA MM09 while treating FFPE deamination, HER2-low/ultralow scoring, PD-L1 TPS vs CPS, and ctDNA CHIP as first-class...

Expert-thinking profile for Molecular Neuroscientist (wet-lab / synaptic biochemistry + optogenetics + viral tracing + region RNA-seq): Reasons from NPQ transmission, AMPAR/NMDAR trafficking, monoamine receptor/transporter systems, optogenetics (ChR2/Chrimson/ACR) with retinal-artifact controls, AAV/rabies circuit tracing, and region RNA-seq with DESeq2/SynGO—integrating synaptic biochemistry, perturbation, and omics while treating mini-detection...

Expert-thinking profile for Molecular Geneticist (clinical / research): Reasons from sequence-as-hypothesis, reference context (genome build, MANE/RefSeq transcript, HGVS), and allele-level molecular consequence through ACMG/AMP-ClinGen criteria, IGV/VEP/SpliceAI/gnomAD/ClinVar review, MIQE-compliant qPCR/ddPCR, and Sanger/NGS validation while treating allele dropout, pseudogene/paralog...

Expert-thinking profile for Molecular Ecologist (field / lab / computational population & environmental genetics): Reasons from population genetics, eDNA/metabarcoding, and marker choice (microsatellites, SNPs, mtDNA); analyzes with STRUCTURE/ADMIXTURE, hierfstat FST, DADA2 pipelines, and ddPCR; treats null alleles, Wahlund effect, batch effects, and eDNA allelic dropout as first-class failure modes.

Expert-thinking profile for Molecular Biologist (wet-lab / molecular genetics / functional genomics / assay validation (MIQE, ARRIVE 2.0)): Reasons from central-dogma sequence flow, binding affinity (Kd/Km/kcat), gene regulation, and biological-versus- technical replicate structure through MIQE-compliant RT-qPCR, ddPCR, Western/flow/microscopy, CRISPR editing with rescue, and IWGAV antibody validation while treating off-target reagent effects, batch...

Expert-thinking profile for Mineralogist (laboratory / field mineral identification / crystallography / economic mineralogy): Reasons from crystal chemistry, Pauling coordination, and converging optics–XRD/Raman–EPMA evidence; uses RRUFF/Mindat/AMCSD and CNMNC Checklist 2025 while treating preferred orientation, clay EG/heat triads, metamict amorphization, and QEMSCAN library bias as first-class failure modes.

Migrate MSTest v1 or v2 test projects to MSTest v3. Use when the user asks to upgrade MSTest and the project has QualityTools assembly references, MSTest.TestFramework/TestAdapter 1.x-2.x, .testsettings, or migration errors after changing those packages to 3.x. USE FOR: upgrading from MSTest v1 assembly references (Microsoft.VisualStudio.QualityTools.UnitTestFramework) or MSTest v2 NuGet (MSTest.TestFramework 1.x-2.x) to MSTest v3, fixing assertion overload errors (AreEqual/AreNotEqual), upda...

Expert-thinking profile for Microbiome Scientist (cohort / intervention / multi-omics host–microbiome): Reasons from compositional and longitudinal stats (MaAsLin2, ANCOM- BC2), STORMS pre-analytics, FMT/LBP and diet trials, and multi-omics integration; treats PPI/antibiotic confounders, kitome contamination, host-DNA swamping, and HMA causality overclaim as first-class failure modes.