Evaluates large language models on a comprehensive taxonomy of real-world clinical workflows, covering tasks like clinical note generation, patient communication, medical research assistance, clinical decision support, and administration/workflow. It probes both closed-ended factual/reasoning tasks and open-ended free-text generation capabilities in medical domains. Use when the user wants to benchmark on MedHELM, or asks about evaluating this task. Reports Macro-average performance.
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---
name: medhelm-eval
description: Evaluates large language models on a comprehensive taxonomy of real-world clinical workflows, covering tasks like clinical note generation, patient communication, medical research assistance, clinical decision support, and administration/workflow. It probes both closed-ended factual/reasoning tasks and open-ended free-text generation capabilities in medical domains. Use when the user wants to benchmark on MedHELM, or asks about evaluating this task. Reports Macro-average performance.
metadata:
skill_kind: dataset_eval
source_arxiv: 2505.23802
bibtex_key: bedi2025medhelm
confidence: high
---
# medhelm-eval
> MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks — Suhana Bedi et al. (arXiv:2505.23802, 2025)
## What this evaluates
Evaluates large language models on a comprehensive taxonomy of real-world clinical workflows, covering tasks like clinical note generation, patient communication, medical research assistance, clinical decision support, and administration/workflow. It probes both closed-ended factual/reasoning tasks and open-ended free-text generation capabilities in medical domains.
## Datasets
- **MedHELM** — total ?; splits: test (-1)
## Metrics
- `Macro-average performance` **(primary)** — range: [0, 1]
- Average of normalized performance scores across all 35 benchmarks.
- `Win-rate` — range: [0, 1]
- Proportion of pairwise comparisons where a model outperforms another across all 35 benchmarks.
- `LLM-jury score` — range: [0, 1]
- Average normalized score assigned by three frontier LLMs to open-ended model outputs.
- `exact-match accuracy` — range: [0, 1]
- Binary indicator of whether the model's output exactly matches the ground truth answer.
- `F1 score` — range: [0, 1]
- Harmonic mean of precision and recall for extracting ICD-10 codes from clinical notes.
## Input / output format
**Input**: Prompt containing a medical task description, patient notes, or clinical question, varying by benchmark (closed-ended multiple choice or open-ended generation).
**Output**: Model-generated response: either a selected answer choice for closed-ended tasks or free-text generation for open-ended tasks.
## Scoring recipe
```python
def score(predictions, golds, is_open_ended=False):
if is_open_ended:
jury_scores = [jury_llm.evaluate(pred, gold) for pred, gold in zip(predictions, golds)]
return {'LLM-jury score': mean(jury_scores)}
else:
em = [1 if pred == gold else 0 for pred, gold in zip(predictions, golds)]
return {'exact-match accuracy': mean(em)}
# Macro-average is computed by averaging normalized scores across all 35 benchmarks.
# Win-rate is computed via pairwise comparisons across all benchmarks.
```
## Common pitfalls
- Win-rate is calculated as pairwise comparisons across all 35 benchmarks, not a simple average of individual benchmark scores.
- LLM-jury scores are aggregated from three frontier LLMs and validated against clinician ratings using ICC(3,k), not standard lexical metrics like ROUGE-L.
- Cost estimates are upper-bound based on maximum output token usage, not actual inference costs.
## Evidence (verbatim from paper)
> Win-rate represents the proportion of pairwise comparisons where each model achieved superior performance across all 35 benchmarks (possible range: 0-1). Win standard deviation (SD) measures how consistently a model wins (lower values = more consistent). Macro-avg is the average performance score across all 35 benchmarks.
## Citation
```bibtex
@misc{bedi2025medhelm,
title={MedHELM: Holistic Evaluation of Large Language Models for Medical Tasks},
author={Suhana Bedi et al.},
year={2025},
note={arXiv:2505.23802}
}
```
- arXiv: 2505.23802