Research

Expert-thinking profile for Quantum Chemist (computational / ab initio electronic structure theory): Reasons from the Schrödinger equation through HF, MP2/CCSD(T)/CBS, and multireference (CASSCF/CASPT2); uses ORCA/Psi4/Gaussian with GMTKN55/WTMAD-4 validation, T1/D1 diagnostics, Helgaker CBS extrapolation, and BSSE/spin-contamination checks while treating SCF near-degeneracy, intruder states, and global-vs-local...

Expert-thinking profile for Quality / Six Sigma Engineer (DMAIC/DMADV / SPC & capability / measurement systems analysis / APQP-PPAP automotive / ISO 9001 auditing): Reasons from process variation, defect operational definitions, and customer-critical characteristics through Shewhart control charts, Gage R&R (%GRR, ndc), Cp/Cpk and Pp/Ppk capability, DMAIC tollgates, and AIAG PPAP/PFMEA in Minitab or JMP while treating Cpk on unstable processes, attribute data forced as normal...

Expert-thinking profile for Pure Mathematician (proof-theoretic / theorem-proof / formal verification (Lean 4/mathlib, Coq, Isabelle) / MSC-classified): Reasons from definitions, axioms, and proved theorems through lemma-ladder proof strategies, computer algebra (SageMath, GAP, Magma) and proof assistants (Lean 4/mathlib, Coq, Isabelle/HOL) checked against MathSciNet/zbMATH and OEIS, while treating hidden hypotheses, circular reasoning, unjustified w.l.o.g. steps, and...

Search PubMed for a gene name or disease term and generate a structured research briefing of the top recent English-language

Search PubMed for scientific literature. Use when the user asks to find papers, search literature, look up research, find publications, or asks about recent studies. Triggers on "pubmed", "papers", "literature", "publications", "research on", "studies about".

Expert-thinking profile for Public Health Scientist (population health / surveillance / program evaluation / policy): Reasons from the 10 Essential Public Health Services, epidemiologic triad, and SDOH; runs outbreak field investigations, NSSP syndromic and NNDSS surveillance, BRFSS/WONDER complex-survey analysis, CDC Framework and RE-AIM program evaluation, PAF/PIF policy quantification, and Kass ethics review.

Expert-thinking profile for Psychophysicist (laboratory / psychophysics & perception): Reasons from psychometric functions, staircase/MLE threshold procedures, signal- detection theory, and calibrated display/audio transducers while treating timing jitter, adaptation, and criterion/sensitivity conflation as first-class failure modes.

Expert-thinking profile for Protistologist (microscopy / 18S metabarcoding (PR2/SILVA) / culture & barcoding / HAB monitoring / paleoecology): Reasons from eukaryotic microbial diversity, trophic mode, and morphology-molecule integration through Utermöhl counts, SEM, 18S/V4 metabarcoding with PR2/SILVA, and IQ-TREE/MAFFT phylogenies while treating chimeric ASVs, kleptoplastic mixotroph misclassification, dinoflagellate multi-copy rRNA inflation, and...

Expert-thinking profile for Programming Languages Researcher (formal semantics / type systems / mechanized metatheory (Coq/Ott) / verification / POPL-PLDI): Reasons from operational semantics, type-theoretic invariants, and soundness as preservation-plus- progress through Ott/LN-defined calculi, Coq/Isabelle/Agda mechanization, Hindley- Milner inference, and abstract-interpretation Galois connections while treating stuck terms, blame escaping onto well-typed pure terms...

Unified personal genomic profile report — reads a PatientProfile JSON and synthesizes all skill results into

Expert-thinking profile for Process Engineer (process design / simulation / commissioning & plant troubleshooting): Reasons from conservation laws, CSTR/PFR selectivity and RTD/Da scale-up through BFD→PFD→P&ID/HAZOP/LOPA/SIL, Aspen Plus/HYSYS HMB, API 520/521 relief and LMTD/F_t exchanger sizing, and lab→pilot→plant commissioning while treating frozen-design violations, simulation-without-data, and BPCS/IPL conflation as...

Expert-thinking profile for Process Chemist (API/route development / scale-up & reaction engineering / crystallization & PAT / regulatory (ICH Q8-Q11, M7, QbD)): Reasons from mass and energy balances, impurity fate maps, and supersaturation trajectories through RC1 calorimetry, DoE in JMP/MODDE, FBRM/XRPD crystallization tracking, and ICH Q8/Q9/Q11 control strategy while treating exotherm runaway at plant jacket capacity, ICH M7 genotoxic carry-over, polymorph shifts on scale...

Expert-thinking profile for Probabilist (theoretical / computational probability): Reasons from Kolmogorov measure spaces through LLN/CLT, martingales, coupling, concentration/LDP, and Lévy/Feller/Itô calculus; uses Durrett/Kallenberg canon, Sage/NumPy/PyMC simulation, and R̂/ESS/IS diagnostics while treating a.s. vs sure, Borel conditioning, OST misuse, and importance-weight explosion as...

Expert-thinking profile for Primatologist (field / observational ethology / conservation / comparative & captive research): Reasons from Tinbergen questions, habituation trade-offs, and phylogenetic comparative trees (TimeTree, Craig 2024) through focal/scan ethograms (BORIS, κ), Raven/Praat vocal repertoires, IUCN SSC great-ape surveys (A.P.E.S.), and CITES/IACUC/IPS health protocols while treating pseudoreplication, anthroponotic...

Expert-thinking profile for Precision Medicine Scientist (clinical / research): Reasons from molecular profiles, tiered actionability, tumor purity, and clonal architecture through OncoKB and AMP/ASCO/CAP tiers, Mutect2/STAR-Fusion calling, IGV review, and CPIC pharmacogenomic guidelines while treating FFPE C-to-T deamination, CHIP mimicking somatic drivers, immortal-time bias in real-world data...

Runs a pre-submission review of a technical paper across five dimensions: macro logic, writing details, English grammar, LaTeX formatting, and figure quality. Uses a reviewer-style severity taxonomy (CRITICAL / MAJOR / MINOR) and flags banned AI-tone vocabulary and em-dash misuse. Use when the user asks to 'review this paper', 'audit before submission', 'check the draft', 'find issues', 'proofread', or within one week of a submission deadline.

Create research posters using HTML/CSS that can be exported to PDF or PPTX. Use this skill ONLY when the user explicitly requests PowerPoint/PPTX poster format. For standard research posters, use latex-posters instead. This skill provides modern web-based poster design with responsive layouts and easy visual integration.

Analyze product data and manage product tooling in PostHog. Use when the user wants product analytics or insights, HogQL/SQL queries, feature flags, experiments and A/B tests, error tracking, session replay, surveys, LLM analytics, dashboards, data warehouse, or PostHog documentation.

Expert-thinking profile for Polymer Scientist (synthesis / characterization / rheology-morphology / polymer processing / failure analysis): Reasons from molecular weight distribution, Tg/Tm and crystallinity, viscoelasticity, and phase behavior through GPC/SEC, DSC heat-cool-heat, capillary and oscillatory rheology, WAXD/SAXS, and DMA while treating thermal-history erasure, moisture hydrolysis, incomplete cure, and wrong-grade-lot artifacts as first-class...

Expert-thinking profile for Polymer Chemist (wet-lab / synthetic polymer chemistry): Designs and interprets polymer synthesis, characterization, and structure–property relationships from mechanism (chain-growth, step-growth, RDRP, ROMP) through absolute MW verification to application-relevant thermal and rheological data.

Expert-thinking profile for Plant Physiologist (wet-lab / greenhouse / field plant physiology): Reasons from source–sink carbon–water balance, FvCB A–Ci and Ball–Berry gs models, LI-COR/PAM gas exchange, Scholander Ψ, drought–salt–heat signaling, and MIAPPE/Phytozome workflows while treating chamber leakage, pot-bound roots, and Fv/Fm–yield conflation as first-class failure modes.

Expert-thinking profile for Plant Pathologist (diagnostic clinic / field epidemiology / wet-lab & molecular phytopathology): Reasons from the disease triangle, sign vs. symptom, and trophic strategy (biotroph/necrotroph/hemibiotroph); runs clinic-to-Koch workflows (TWA isolation, Phytophthora pear baiting, Baermann nematodes, EPPO PM7/qPCR with matrix-specific Ct cutoffs) and epidemic analysis (AUDPC/AUDPS, Vanderplank parameters, GLMMs)...

Expert-thinking profile for Planetary Scientist (solar-system / remote-sensing & in situ / exoplanet detection-characterization / mission archives (PDS, SPICE)): Expert profile for planetary scientist — see AGENTS.md for field-specific methods and failure modes.

Expert-thinking profile for Physician-Scientist (clinical / translational / basic and patient-oriented research): Reasons across the bedside–bench cycle and T0–T4 spectrum; navigates PSTP/ABIM pathways, K08/K23/R01 funding, IRB/IND/IDE sponsor-investigator duties, and CONSORT/SPIRIT reporting while treating protected-time loss and preclinical irreproducibility as first-class failure modes.